KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZCCHC8
All Species:
9.7
Human Site:
S690
Identified Species:
16.41
UniProt:
Q6NZY4
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NZY4
NP_060082.2
707
78577
S690
G
M
Y
L
R
I
R
S
L
L
K
N
S
P
R
Chimpanzee
Pan troglodytes
XP_509445
540
59236
L524
M
Y
L
R
I
R
S
L
L
K
N
S
P
R
N
Rhesus Macaque
Macaca mulatta
XP_001099406
707
78532
S690
G
M
Y
L
R
I
R
S
L
L
K
N
S
P
R
Dog
Lupus familis
XP_534658
709
78944
N692
G
M
Y
L
R
I
R
N
L
L
K
N
S
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYA6
709
78007
N692
G
M
Y
L
R
I
R
N
L
L
K
N
S
P
R
Rat
Rattus norvegicus
NP_001099399
476
51796
L460
M
Y
L
R
I
R
N
L
L
K
N
S
P
R
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506640
716
78801
S699
G
V
Y
L
R
I
R
S
L
L
K
N
S
P
R
Chicken
Gallus gallus
Q5F3D1
613
68449
I597
S
T
G
T
Y
L
R
I
R
S
V
L
K
N
S
Frog
Xenopus laevis
Q6DD45
743
82926
G727
G
V
Y
L
R
L
R
G
L
L
K
N
S
P
R
Zebra Danio
Brachydanio rerio
NP_001077287
692
77048
L674
A
E
A
T
G
V
Y
L
K
I
R
D
L
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q2PE14
553
62387
D537
G
K
Y
E
Q
M
K
D
L
L
K
N
V
R
E
Honey Bee
Apis mellifera
XP_001122586
556
62911
S540
N
Y
E
N
L
P
D
S
T
G
K
Y
E
Q
M
Nematode Worm
Caenorhab. elegans
P34656
453
51815
A437
S
S
N
N
S
G
T
A
K
N
K
N
N
Q
N
Sea Urchin
Strong. purpuratus
XP_798020
626
69735
K610
F
E
A
D
E
P
K
K
K
G
I
F
R
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.1
95.3
87.5
N.A.
80.8
54.5
N.A.
74.8
57.2
55.9
47.8
N.A.
25.8
25.6
22.7
27.4
Protein Similarity:
100
75.2
97.7
92.8
N.A.
88.1
59.2
N.A.
82.8
67.3
69.8
65
N.A.
42.8
42.5
38
45.9
P-Site Identity:
100
6.6
100
93.3
N.A.
93.3
6.6
N.A.
93.3
6.6
80
0
N.A.
40
13.3
13.3
0
P-Site Similarity:
100
13.3
100
100
N.A.
100
13.3
N.A.
100
13.3
93.3
33.3
N.A.
60
13.3
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
15
0
0
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
8
8
0
0
0
8
0
0
0
% D
% Glu:
0
15
8
8
8
0
0
0
0
0
0
0
8
0
8
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
50
0
8
0
8
8
0
8
0
15
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
15
36
0
8
0
8
8
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
15
8
22
15
65
0
8
8
8
% K
% Leu:
0
0
15
43
8
15
0
22
65
50
0
8
8
8
8
% L
% Met:
15
29
0
0
0
8
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
0
8
15
0
0
8
15
0
8
15
58
8
8
22
% N
% Pro:
0
0
0
0
0
15
0
0
0
0
0
0
15
43
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
0
15
0
% Q
% Arg:
0
0
0
15
43
15
50
0
8
0
8
0
8
22
43
% R
% Ser:
15
8
0
0
8
0
8
29
0
8
0
15
43
0
8
% S
% Thr:
0
8
0
15
0
0
8
0
8
0
0
0
0
0
0
% T
% Val:
0
15
0
0
0
8
0
0
0
0
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
22
50
0
8
0
8
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _